Document Detail

Severe immune hemolytic anemia associated with prophylactic use of cefotetan in obstetric and gynecologic procedures.
MedLine Citation:
PMID:  10411803     Owner:  NLM     Status:  MEDLINE    
Second- and third-generation cephalosporins, especially cefotetan, are increasingly associated with severe, sometimes fatal immune hemolytic anemia. We noticed that 10 of our 35 cases of cefotetan-induced hemolytic anemias were in patients who had received cefotetan prophylactically for obstetric and gynecologic procedures. Eight of these cases of severe immune hemolytic anemia are described.
G Garratty; R M Leger; P A Arndt
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  181     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1999 Jul 
Date Detail:
Created Date:  1999-08-19     Completed Date:  1999-08-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  103-4     Citation Subset:  AIM; IM    
American Red Cross Blood Services, Southern California Region, Los Angeles, California, USA.
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MeSH Terms
Anemia, Hemolytic, Autoimmune / chemically induced*
Antibiotic Prophylaxis / adverse effects*
Cefotetan / adverse effects*
Cephamycins / adverse effects*
Obstetric Surgical Procedures
Severity of Illness Index
Reg. No./Substance:
0/Cephamycins; 69712-56-7/Cefotetan

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