Document Detail


Severe hyponatraemia secondary to beer potomania complicated by central pontine myelinolysis.
MedLine Citation:
PMID:  10622059     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A case of severe hyponatraemia in a 56-year-old male alcohol misuser secondary to beer potomania is presented. In view of severe volume depletion and the patient's inability to drink, normal saline was cautiously infused. Despite initial improvement, he subsequently deteriorated neurologically. Magnetic resonance imaging demonstrated the classical lesion of central pontine myelinolysis (CPM). The rate of correction of plasma sodium was within limits normally considered safe. Beer potomania should be considered as a cause of hyponatraemia in alcohol misusers. Recognition is important as the electrolyte imbalance repairs simply with cessation of alcohol intake and institution of normal diet. Correction of chronic hyponatraemia by infusion of normal or hypertonic saline should not be attempted unless life-threatening neurological complications supervene. When the balance of risks favours correction, caution should be exercised, as CPM may occur. Although a rate of correction of plasma sodium of up to 10 mM per 24-hour period has been associated with a low risk of precipitating CPM, this case illustrates that a completely safe rate of correction probably cannot be defined.
Authors:
J Kelly; W Wassif; J Mitchard; W N Gardner
Related Documents :
6759489 - Plasma prostaglandins, renin, and catecholamines at rest and during exercise in hyperte...
6386559 - The effect of starvation on the gastro-entero-pancreatic hormonal and metabolic respons...
23365989 - A system for the model based emergency detection and communication for the telerehabili...
1748109 - Administration of branched-chain amino acids during sustained exercise--effects on perf...
23548359 - Pathology and causes of death of stranded cetaceans in the canary islands (1999-2005).
20347489 - Exercise-induced release of cytokines in patients with major depressive disorder.
8900829 - Dynamic work in cold.
1490949 - Alterations of filtration coefficients in pulmonary edema of different pathogenesis.
2614879 - Oxygen therapy and vasodilator therapy in patients with chronic lung disease: the effec...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International journal of clinical practice     Volume:  52     ISSN:  1368-5031     ISO Abbreviation:  Int. J. Clin. Pract.     Publication Date:    1998 Nov-Dec
Date Detail:
Created Date:  2000-01-28     Completed Date:  2000-01-28     Revised Date:  2007-02-14    
Medline Journal Info:
Nlm Unique ID:  9712381     Medline TA:  Int J Clin Pract     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  585-7     Citation Subset:  IM    
Affiliation:
Department of Healthcare for the Elderly, King's College Hospital, London, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Alcoholism / complications*
Beer
Humans
Hyponatremia / drug therapy*
Magnetic Resonance Imaging
Male
Middle Aged
Myelinolysis, Central Pontine / diagnosis,  etiology*
Risk Assessment
Saline Solution, Hypertonic / adverse effects*
Chemical
Reg. No./Substance:
0/Saline Solution, Hypertonic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Non-inpatient use of teicoplanin.
Next Document:  Ulcerated dystrophic calcinosis cutis secondary to localised linear scleroderma.