| Severe hypertriglyceridemia-induced pancreatitis during pregnancy. | |
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MedLine Citation:
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PMID: 16623082 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Chylomicronemia syndrome is a rare disorder characterized by the presence of chylomicrons in the fasting state. An acute and potentially life-threatening complication of chyiomicronemia syndrome is severe acute pancreatitis. We report a case of a 24-year-old primigravida with severe hypertriglyceridemia-induced pancreatitis. We reviewed the clinical course and treatment of hypertriglyceridemia-induced pancreatitis. She was admitted in the 37th week of gestation with severe abdominal pain, which was radiating to the back, and having uterine contractions. Cesarean delivery was performed under spinal anesthesia, and a healthy male infant was born. Intraoperative findings included milky peritoneal fluid collection. Elevated pancreatic enzymes with significant hypertriglyceridemia (10,092 mg/dL) suggesting acute pancreatitis were also found on chemical analysis. The diagnosis of acute pancreatitis was confirmed by computed tomography scan. Treatment with continuous intravenous insulin--glucose, cessation of oral intake, and nasogastric decompression--dramatically decreased the triglyceride levels to 608 mg/dL within five days. She was discharged as symptom free with strict dietary intervention after 10 days. Intravenous insulin is a low-cost and effective alternative treatment in hypertriglyceridemia-induced pancreatitis during pregnancy. To our knowledge, such a high triglyceride level has not previously been reported in pregnancy. |
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Authors:
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Alptekin Gürsoy; Mustafa Kulaksizoglu; Mustafa Sahin; Derun Taner Ertugrul; Feyza Ozer; Neslihan Bascil Tutuncu; Nilgun Guvener Demirag |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of the National Medical Association Volume: 98 ISSN: 0027-9684 ISO Abbreviation: J Natl Med Assoc Publication Date: 2006 Apr |
Date Detail:
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Created Date: 2006-04-20 Completed Date: 2006-06-09 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 7503090 Medline TA: J Natl Med Assoc Country: United States |
Other Details:
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Languages: eng Pagination: 655-7 Citation Subset: IM |
Affiliation:
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Faculty of Medicine, Department of Endocrinology and Metabolism, Baskent University, Ankara, Turkey. alptekingursoy@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adult Cesarean Section Cholesterol / blood Female Glucose / administration & dosage, therapeutic use Humans Hypertriglyceridemia / complications*, diet therapy Infusions, Intravenous Insulin / administration & dosage, therapeutic use Pancreatitis / blood, drug therapy, etiology* Pregnancy Pregnancy Complications* / surgery Pregnancy Trimester, Third Triglycerides / blood |
| Chemical | |
Reg. No./Substance:
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0/Triglycerides; 11061-68-0/Insulin; 50-99-7/Glucose; 57-88-5/Cholesterol |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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