| Severe gastrointestinal bleeding in a uremic patient treated with estrogen-progesterone therapy. | |
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MedLine Citation:
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PMID: 10467929 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Gastrointestinal bleeding is a frequent complication in hemodialysis patients; angiodysplasia is a potential cause, with a higher incidence in uremic patients. We describe a case of severe anemia (Hemoglobin up to 3.5 g/dl) secondary to diffuse angiodysplastic lesions in a hemodialysis patient with mixed connective tissue disease. The case is characterised both by the severity of the clinical picture (extension and entity of angiodysplastic lesions, frequency of bleeding episodes) and by the patient's religious faith which made her reject blood transfusions. We underline the efficacy of estrogen-progesterone therapy in view of the modest results obtained with other therapeutic strategies on bleeding. |
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Authors:
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G Mosconi; E Mambelli; F Zanchelli; E Isola; C Perna; A De Pascalis; C Raimondi; M Ventrucci; S Stefoni |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The International journal of artificial organs Volume: 22 ISSN: 0391-3988 ISO Abbreviation: Int J Artif Organs Publication Date: 1999 May |
Date Detail:
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Created Date: 1999-10-20 Completed Date: 1999-10-20 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7802649 Medline TA: Int J Artif Organs Country: ITALY |
Other Details:
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Languages: eng Pagination: 313-6 Citation Subset: IM |
Affiliation:
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Department of Clinical Medicine and Applied Biotechnology, S. Orsola University Hospital, Bologna, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anemia / etiology Angiodysplasia / complications, drug therapy Drug Therapy, Combination Estradiol / administration & dosage, adverse effects, analogs & derivatives* Female Gastrointestinal Hemorrhage / drug therapy*, etiology* Humans Mixed Connective Tissue Disease / complications Norethindrone / administration & dosage*, adverse effects Progesterone Congeners / administration & dosage*, adverse effects Renal Dialysis / adverse effects Uremia / complications*, therapy |
| Chemical | |
Reg. No./Substance:
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0/Progesterone Congeners; 0/ethylenestradiol; 50-28-2/Estradiol; 68-22-4/Norethindrone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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