Document Detail


Severe exfoliative erythema of malnutrition in a child with coexisting coeliac and Hartnup's disease.
MedLine Citation:
PMID:  19018792     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Exfoliative erythema of malnutrition is a collective term for skin lesions caused by a combination of multiple deficiencies in vitamins, microelements, essential fatty acids and amino acids. We report a 3-year-old Iraqi girl with malnutrition due to coexisting coeliac and Hartnup's disease. On admission to hospital, she presented with kwashiorkor, anaemia, hepatitis and hypoalbuminia. She had severe skin changes with erythema, desquamation, erosions and diffuse hyperpigmentation involving the whole integument, particularly the perioral area, trunk and legs. She also had angular cheilitis, glossitis, conjunctivitis and diffuse alopecia. After treatment with a high-protein gluten-free diet and supplementation with vitamins and microelements there was a rapid improvement in the skin lesions. The severity of the skin lesions in this case can be explained by the coexistence of two metabolic diseases causing complex malnutrition.
Authors:
C S Sander; J Hertecant; Y M Abdulrazzaq; T G Berger
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-11-06
Journal Detail:
Title:  Clinical and experimental dermatology     Volume:  34     ISSN:  1365-2230     ISO Abbreviation:  Clin. Exp. Dermatol.     Publication Date:  2009 Mar 
Date Detail:
Created Date:  2009-02-03     Completed Date:  2009-04-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7606847     Medline TA:  Clin Exp Dermatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  178-82     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Tawam Hospital in affiliation with Johns Hopkins Medicine, Al Ain, UAE. csander@tawam-hosp.gov.ae
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MeSH Terms
Descriptor/Qualifier:
Alopecia / complications
Celiac Disease* / complications,  diet therapy,  pathology
Child Nutrition Disorders* / complications,  diet therapy
Child, Preschool
Diet, Gluten-Free
Erythema* / diet therapy,  etiology,  pathology
Female
Glossitis / complications
Glutens / adverse effects*
Hartnup Disease* / complications,  diet therapy,  pathology
Humans
Parents / education
Skin / pathology
Treatment Outcome
Vitamins / administration & dosage
Chemical
Reg. No./Substance:
0/Vitamins; 8002-80-0/Glutens

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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