Document Detail

Severe euthyroid cardiac disease; technique for treatment with radioiodine.
MedLine Citation:
PMID:  13270104     Owner:  NLM     Status:  OLDMEDLINE    
It is possible to safely lower the basal metabolism of patients suffering from severe cardiac disease by administering multiple small doses of radioiodine in order to achieve symptomatic relief. From the present study, multiple small doses of I(131) appeared to be as effective as single or multiple large doses of this material and complications such as thyroiditis, temporary thyrotoxicosis and bone marrow depression were almost always avoided. No damage to the parathyroid glands or the recurrent laryngeal nerve was observed. No radiation sickness developed after therapy.A scintigram of the thyroid gland was useful in determining the size, shape and function of the thyroid gland before and during radioiodine treatment and helped to determine the need for additional treatment. In order to prevent the distressing symptoms of the myxedema state, desiccated thyroid was administered when necessary. In the series of 278 euthyroid patients with severe cardiac disease who were treated with radioactive iodine, results were excellent in 35 per cent of cases and good in 44 per cent. In 21 per cent there was no improvement.
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  California medicine     Volume:  83     ISSN:  0008-1264     ISO Abbreviation:  Calif Med     Publication Date:  1955 Dec 
Date Detail:
Created Date:  1956-12-01     Completed Date:  2003-05-01     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0410260     Medline TA:  Calif Med     Country:  Not Available    
Other Details:
Languages:  eng     Pagination:  412-5     Citation Subset:  OM    
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MeSH Terms
Heart Failure / therapy*
Hypothyroidism / complications*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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