Document Detail

Severe cysticercal meningitis: clinical and imaging characteristics.
MedLine Citation:
PMID:  20065006     Owner:  NLM     Status:  MEDLINE    
In disease-endemic areas, severe cysticercal meningitis (SCM) is characterized by intense inflammatory cerebrospinal fluid (CSF) and negative bacterial and fungal cultures. There have been no systematic studies of SCM. We characterized patients with SCM and compare them with neurocysticercosis (NC) patients with mild CSF abnormalities by conducting a nine-year retrospective review at a neurological referral center. Two groups of patients were compared: group A, those with severe CSF pleocytosis > 1,000 cells/mm(3) (n = 12), and group B, those with CSF pleocytosis <or= 1,000 cells/mm(3) (n = 126). All patients had positive CSF results in an enzyme-linked immunosorbent assay for cysticercal antigens and negative CSF cultures for bacteria, fungi, and mycobacteria. Intracranial hypertension, meningeal signs, CSF hypoglycorrachia, and a longer clinical course of NC were more frequently seen in group A. It is likely that SCM often goes unrecognized. Its correct identification may reduce morbidity and risks of unnecessary surgery in patients with chronic NC and CSF shunts.
Graciela Cárdenas; Helgi Jung; Camilo Ríos; Agnes Fleury; José Luís Soto-Hernández
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of tropical medicine and hygiene     Volume:  82     ISSN:  1476-1645     ISO Abbreviation:  Am. J. Trop. Med. Hyg.     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-01-12     Completed Date:  2010-01-25     Revised Date:  2013-05-31    
Medline Journal Info:
Nlm Unique ID:  0370507     Medline TA:  Am J Trop Med Hyg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  121-5     Citation Subset:  AIM; IM    
Department of Neuropsychopharmacology, Instituto Nacional de Neurología y Neurocirugía, Mexico City, Mexico.
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MeSH Terms
Middle Aged
Neurocysticercosis / pathology*
Retrospective Studies

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