Document Detail

Severe coronary tortuosity and the relationship to significant coronary artery disease.
MedLine Citation:
PMID:  19585899     Owner:  NLM     Status:  MEDLINE    
Severe coronary artery tortuosity on coronary angiogram has not been previously evaluated to determine whether it is associated with coronary artery disease or risk factors for coronary artery disease. A retrospective analysis of all patients who underwent coronary angiography at West Virginia University Hospital during an eight month period was performed. All patients with severe coronary tortuosity (SCT), defined as two consecutive 180 degrees turns by visual estimation in a major epicardial artery, were identified and their medical records reviewed for the presence of coronary artery disease risk factors and presence of significant coronary artery disease. A randomly chosen group of patients who underwent coronary angiography during the same time who did not have SCT was used for a control group. Multivariable analysis using logistic regression was performed to determine predictors of SCT. Severe coronary tortuosity was found in 12.45% of our 1221 patients. Female gender was found to be significantly higher in the tortuosity group of patients compared to the control group (p = 0.039). The presence of severe tortuosity was associated with a statistically significant lower incidence of significant coronary artery disease (p = 0.003). Hypertension, hyperlipidemia, smoking, family history of coronary artery disease, diabetes mellitus, and age > or =65 years were not predictors of SCT. Our study did not find that coronary artery disease risk factors were predictors of coronary tortuosity. Future investigations may provide further insight into the significance or cause of coronary artery tortuosity.
Samuel S Groves; Abnash C Jain; Bradford E Warden; Wissam Gharib; Robert J Beto
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The West Virginia medical journal     Volume:  105     ISSN:  0043-3284     ISO Abbreviation:  W V Med J     Publication Date:    2009 Jul-Aug
Date Detail:
Created Date:  2009-07-09     Completed Date:  2009-08-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0413777     Medline TA:  W V Med J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  14-7     Citation Subset:  IM    
Section of Cardiology, Department of Internal Medicine, WVU School of Medicine, Morgantown, USA.
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MeSH Terms
Coronary Angiography
Coronary Artery Disease / pathology*
Coronary Vessels / pathology*
Multivariate Analysis
Retrospective Studies
Sex Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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