Document Detail


Severe combined immunodeficiency associated with hyperimmunoglobulinaemia E, eosinophilia and impaired neutrophil chemotaxis.
MedLine Citation:
PMID:  7211366     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A boy with severe combined immunodeficiency was found to have coexistent hyperimmunoglobulinaemia E, eosinophilia and impaired neutrophil chemotaxis. Based on the literature, a deficient regulatory function of the T-cell system is proposed as the basic defect leading to the observed impairment of the cellular and humoral immunity and, probably through hyper-immunoglobulinaemia E, to defective neutrophil chemotaxis.
Authors:
B Beck; B Friis; C Heilmann; F K Pedersen; N H Valerius
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta paediatrica Scandinavica     Volume:  69     ISSN:  0001-656X     ISO Abbreviation:  Acta Paediatr Scand     Publication Date:  1980 Nov 
Date Detail:
Created Date:  1981-05-13     Completed Date:  1981-05-13     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0000211     Medline TA:  Acta Paediatr Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  797-801     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Chemotaxis, Leukocyte*
Eosinophilia / complications*
Humans
Hypergammaglobulinemia / complications*
Immunoglobulin E*
Immunologic Deficiency Syndromes / complications*
Infant
Male
Neutrophils
Chemical
Reg. No./Substance:
37341-29-0/Immunoglobulin E

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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