Document Detail

Severe clinical manifestations of primary HIV infection.
MedLine Citation:
PMID:  2575913     Owner:  NLM     Status:  MEDLINE    
Three cases of oesophageal candidiasis in association with primary HIV infection are described. In each case the candidiasis was associated with a decreased number of circulating CD4+ cells and responded well to treatment with ketoconazole. Clinicians should be aware that severe opportunistic infections may develop during this stage of infection, presumably as a result of transient immunodeficiency. We argue that the definition of primary HIV infection should be extended to include severe opportunistic infections and neurologic presentations.
B Tindall; M Hing; P Edwards; T Barnes; A Mackie; D A Cooper
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  AIDS (London, England)     Volume:  3     ISSN:  0269-9370     ISO Abbreviation:  AIDS     Publication Date:  1989 Nov 
Date Detail:
Created Date:  1990-03-16     Completed Date:  1990-03-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8710219     Medline TA:  AIDS     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  747-9     Citation Subset:  IM; X    
NHMRC Special Unit in AIDS Epidemiology and Clinical Research, University of New South Wales, Australia.
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MeSH Terms
CD4-Positive T-Lymphocytes
Candidiasis / complications*,  drug therapy
Esophageal Diseases / complications*,  drug therapy
HIV Infections / complications*
Ketoconazole / therapeutic use
Leukocyte Count
Middle Aged
Opportunistic Infections / complications*,  drug therapy
Reg. No./Substance:

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