| Severe chronic bronchiolitis as the presenting feature of primary Sjögren's syndrome. | |
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MedLine Citation:
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PMID: 21050739 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Sjögren's syndrome is a frequent auto-immune disorder with a pulmonary location in almost 10% of the patients. Although bronchial involvement is very common, most patients only complain of cough and this involvement rarely results in severe symptoms or chronic respiratory failure are rarely observed. We describe here 5 patients with severe chronic bronchiolitis revealing primary Sjögren's syndrome. The lung involvement resulted in chronic bronchorrhea, recurrent sinusitis, diffuse bronchiolar nodules with bronchiectasis on the CT scan, and a severe obstructive airway pattern on lung function tests. Improvement was obtained in 4 patients with combination of inhaled corticosteroids, inhaled long acting beta-agonists, and a low dose of erythromycin. |
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Authors:
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Raphael Borie; Sophie Schneider; Marie-Pierre Debray; Homa Adle-Biasssette; Claire Danel; Anne Bergeron; Xavier Mariette; Michel Aubier; Thomas Papo; Bruno Crestani |
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Publication Detail:
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Type: Journal Article Date: 2010-11-02 |
Journal Detail:
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Title: Respiratory medicine Volume: 105 ISSN: 1532-3064 ISO Abbreviation: Respir Med Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2010-12-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8908438 Medline TA: Respir Med Country: England |
Other Details:
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Languages: eng Pagination: 130-6 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
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Assistance Publique-Hôpitaux de Paris, Hôpital Bichat, Service de Pneumologie A, Centre de Compétence maladies rares pulmonaires, Paris, France; INSERM U700, Université Paris VII Denis Diderot, Paris, France. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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