Document Detail

Severe chronic aortic insufficiency requiring valve replacement: an infrequent complication of Takayasu's disease.
MedLine Citation:
PMID:  16839388     Owner:  NLM     Status:  MEDLINE    
Takayasu's arteritis (TA) is a granulomatous vasculitis of medium and large arteries, which most often presents as pulseless disease due to widespread arterial stenoses. Only the minority of TA patients have aortic valve insufficiency, which is due to aortic root dilatation following aortitis and aneurysm formation. No other cardiac valve is involved. We report a case of Takayasu's disease-related severe aortic insufficiency (AI) in a Filipino woman, which necessitated aortic valve replacement. It is important to consider TA in the differential diagnosis of AI in young women, particularly those with early-onset systemic hypertension and pulse deficits. Early diagnosis and therapy of TA can improve outcomes.
Jennifer Brady; Barry C Esrig; Kamran Hamirani; Ada Baisre; Muhamed Saric
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Echocardiography (Mount Kisco, N.Y.)     Volume:  23     ISSN:  0742-2822     ISO Abbreviation:  Echocardiography     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-07-14     Completed Date:  2006-12-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8511187     Medline TA:  Echocardiography     Country:  United States    
Other Details:
Languages:  eng     Pagination:  495-8     Citation Subset:  IM    
Department of Medecine, New Jersey Medical School, Newark, New Jersey 07103, USA.
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MeSH Terms
Aortic Valve Insufficiency / etiology*,  surgery*,  ultrasonography
Diagnosis, Differential
Echocardiography, Doppler, Color
Heart Valve Prosthesis Implantation*
Takayasu Arteritis / complications*

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