Document Detail


Severe asthma with fungal sensitization: a case report and review of literature.
MedLine Citation:
PMID:  20100013     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There is a substantial body of evidence supporting an association between asthma severity and fungal exposure and sensitization. Fungal allergens are a recognized risk factor for severe asthma. We describe the case of a 44-year-old asthmatic whose asthma control deteriorated after moving to a new flat with walls covered in mould. Allergic bronchopulmonary aspergillosis was excluded. Although sensitization to Candida was demonstrated by a positive Candida-specific radioallergosorbent test, the patient did not entirely satisfy the criteria for a diagnosis of allergic bronchopulmonary candidiasis. The patient's asthma control improved after engaging in a monthly washing regimen of the walls. This case further demonstrates the association between fungal sensitization and asthma severity. The term severe asthma with fungal sensitization has been recently coined to describe this phenomenon.
Authors:
Yasser Madani; Andrew Barlow; Furqan Taher
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The Journal of asthma : official journal of the Association for the Care of Asthma     Volume:  47     ISSN:  1532-4303     ISO Abbreviation:  J Asthma     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-01-26     Completed Date:  2010-02-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106454     Medline TA:  J Asthma     Country:  England    
Other Details:
Languages:  eng     Pagination:  2-6     Citation Subset:  IM    
Affiliation:
Department of Respiratory Medicine, Watford General Hospital, Watford, Hertfordshire, WD18 0HB, United Kingdom. yasser.madani@doctors.org.uk
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MeSH Terms
Descriptor/Qualifier:
Adult
Air Pollution, Indoor / adverse effects
Asthma / immunology*,  physiopathology*,  radiography,  therapy
Candida albicans / immunology
Female
Fungi / immunology*
Humans
Immunoglobulin E / blood,  immunology
Precipitins / blood,  immunology
Chemical
Reg. No./Substance:
0/Precipitins; 37341-29-0/Immunoglobulin E

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