Document Detail

Severe anaemia in pregnancy: a problem of primigravidae in rural Zaire.
MedLine Citation:
PMID:  1801367     Owner:  NLM     Status:  MEDLINE    
Haemoglobin levels were measured in 2950 pregnant women attending antenatal clinics in Kimpese, Bas Zaire. 72% were suffering from moderate anaemia (haemoglobin (Hb) 7-11 g/dl) and 3.7% from severe anaemia (Hb less than 7 g/dl) at their first visit, before receiving any haematinics or anti-malarial prophylaxis. Haemoglobin levels rose with both increasing parity (P less than 0.001) and age. Multiple regression analysis revealed that parity was significant but age was not. The fall in haemoglobin early in the second trimester was greatest in primigravidae and diminished with successive pregnancies until the fourth. One in 6 primigravidae approached labour with a haemoglobin level less than 7.7 g/dl. Thick blood smears were examined from 379 women who presented in the first and second trimester. 70% of primigravidae had malaria parasitaemia, compared with 13% of multigravidae (P less than 0.001). Early malaria prophylaxis in the first 2 pregnancies is an important primary health care objective if the contribution of malaria to the significant fall in haemoglobin in the second trimester is to be averted.
D J Jackson; E B Klee; S D Green; J L Mokili; R A Elton; W A Cutting
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Transactions of the Royal Society of Tropical Medicine and Hygiene     Volume:  85     ISSN:  0035-9203     ISO Abbreviation:  Trans. R. Soc. Trop. Med. Hyg.     Publication Date:    1991 Nov-Dec
Date Detail:
Created Date:  1992-04-20     Completed Date:  1992-04-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7506129     Medline TA:  Trans R Soc Trop Med Hyg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  829-32     Citation Subset:  IM; X    
Department of Child Life and Health, University of Edinburgh, UK.
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MeSH Terms
Acquired Immunodeficiency Syndrome / complications
Age Factors
Anemia / etiology*
Democratic Republic of the Congo
Hemoglobins / analysis
Malaria / blood,  complications
Pregnancy Complications, Hematologic / etiology*
Rural Population
Time Factors
Reg. No./Substance:

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