Document Detail


Severe amiodarone-induced hypothyroidism in an infant.
MedLine Citation:
PMID:  20453707     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
OBJECTIVE: To report a case of postnatal, postoperative amiodarone-induced hypothyroidism in an infant with a congenital heart defect.
DESIGN: Case report and literature review.
SETTING: Pediatric intensive care unit at a freestanding tertiary care children's hospital.
PATIENT: At 7 wks of age, a female infant with a congenital heart defect was confirmed to have profound hypothyroidism after amiodarone administration for a postoperative cardiac arrhythmia.
INTERVENTIONS: Levothyroxine treatment.
MEASUREMENTS AND MAIN RESULTS: Thyroid function tests were regularly performed to guide levothyroxine dosing. Thyroid hormone replacement was discontinued after the infant had been off amiodarone for 6 mos.
CONCLUSIONS: Given the potential adverse developmental consequences associated with hypothyroidism during infancy and early childhood, thyroid function tests should be carefully monitored in any infant treated with amiodarone.
Authors:
Karen Trudel; Shubhayan Sanatani; Constadina Panagiotopoulos
Related Documents :
11279667 - Comparative view of pineal gland morphology of nocturnal and diurnal birds of tropical ...
319467 - Iodinated silicone-an antibacterial alloplastic material.
11332167 - Antenatal magnesium sulphate exposure is associated with prolonged parathyroid hormone ...
6680497 - Comparative studies on immunological characteristics of iddm among asian populations.
8469007 - The use of "nonanatomic" pulmonary resection in infants with extensive congenital adeno...
10906017 - Hospitalisation for rsv infection in ex-preterm infants-implications for use of rsv imm...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies     Volume:  12     ISSN:  1529-7535     ISO Abbreviation:  Pediatr Crit Care Med     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100954653     Medline TA:  Pediatr Crit Care Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e43-5     Citation Subset:  IM    
Affiliation:
Division of Cardiology, University of British Columbia and British Columbia Children's Hospital, Vancouver, BC, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Effect of continuous veno-venous hemodiafiltration on endotoxin-induced acute lung injury of the pig...
Next Document:  Lack of increase in vancomycin resistance of pediatric methicillin-resistant Staphylococcus aureus I...