Document Detail


Severe accidental hypothermia with or without hemodynamic instability: rewarming without the use of extracorporeal circulation.
MedLine Citation:
PMID:  12212366     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The optimal rewarming technique for patients in deep accidental hypothermia with core temperatures below 28 degrees C is not established. Several authors believe that extracorporeal rewarming is essential, especially for patients with hemodynamic instability. Others believe that invasive rewarming ought to be reserved for patients in cardiac arrest. We describe our experience with a strictly conservative technique without the use of invasive rewarming devices in patients with severe accidental hypothermia and a sustained perfusion rhythm. METHODS: A cohort study extending from 1991 to 2000, including all patients received at the emergency department of the University Hospital of Vienna with severe hypothermia, a core temperature of maximum 28 degrees C and no preclinical cardiac arrest. RESULTS: 36 patients with deep hypothermia were included in the study. Their core temperatures ranged from 20.2 degrees C to 28 degrees C; the median temperature was 25.75 degrees C (25th and 75th percentile, 24.2/27.3). Fourteen patients were intoxicated and their multimorbidity was high. All of 19 patients with stable hemodynamics and 14 of 17 patients with unstable hemodynamics were successfully rewarmed to normothermia with warmed infusions, inhalation rewarming and forced air rewarming. The rewarming process took 9.5 hours (8/10.5) and required a volume load of 4820 ml (2735/5770). The rewarming rate was 1.09 degrees C per hour (0.94/1.25). Although 92% of the patients were successfully rewarmed to normothermia, in-hospital mortality was 42%, but was largely related to comorbidity. DISCUSSION: A conservative approach is highly successful in achieving normothermia in patients with deep hypothermia with or without stable hemodynamics. In-hospital mortality of severe accidental hypothermia in urban conditions is high; comorbidity might play a major role. The influence of the rewarming strategy on late in-hospital mortality remains unclear.
Authors:
Martin Röggla; Martin Frossard; Andreas Wagner; Michael Holzer; Andreas Bur; Georg Röggla
Related Documents :
12887336 - Ultrastructure of the gingiva in cardiac patients treated with or without calcium chann...
11943526 - Implementing acc/aha guidelines for the preoperative management of patients with corona...
16244846 - A stochastic control program to predict outcome and to support therapeutic decisions: a...
17491216 - Therapeutic hypothermia for comatose survivors after cardiac arrest.
19093206 - Discriminative value of anorectal manometry in clinical practice.
136916 - In vitro and in vivo studies with thymosin in cancer patients.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Wiener klinische Wochenschrift     Volume:  114     ISSN:  0043-5325     ISO Abbreviation:  Wien. Klin. Wochenschr.     Publication Date:  2002 May 
Date Detail:
Created Date:  2002-09-05     Completed Date:  2002-10-29     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  21620870R     Medline TA:  Wien Klin Wochenschr     Country:  Austria    
Other Details:
Languages:  eng     Pagination:  315-20     Citation Subset:  IM    
Affiliation:
Department of Emergency Medicine, University Clinics of Vienna, Austria.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Austria
Body Temperature / physiology
Cause of Death
Cohort Studies
Female
Hemodynamics / physiology*
Hospital Mortality
Humans
Hypothermia / mortality,  physiopathology,  therapy*
Male
Middle Aged
Retrospective Studies
Rewarming / methods*
Survival Rate
Comments/Corrections
Comment In:
Wien Klin Wochenschr. 2002 May 15;114(8-9):287-8   [PMID:  12212361 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Is hypertension a major risk factor in aneurysmal subarachnoid hemorrhage?
Next Document:  Insulin resistance and androgens in healthy women with different body fat distributions.