| Severe Thrombocytopenia and Hemorrhagic Diathesis due to Brucellosis. | |
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MedLine Citation:
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PMID: 22519380 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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BACKGROUND: We aimed to examine cases of brucellosis that presented with severe thrombocytopenia and hemorrhagic diathesis. METHODS: A total of 10 brucellosis cases with severe thrombocytopenia were included in this case-series study. Patients' files were reviewed for their clinical and laboratory findings, as well as clinical outcomes and complications. Platelet counts of < 20000/mm³ were diagnosed as severe thrombocytopenia. RESULTS: The lowest thrombocyte count was 3000/mm³ while the highest was 19000/mm³ (mean: 12000/mm³). Patients had the following symptoms: epistaxis (7 cases), petechia with epistaxis (4 cases), bleeding gums (3 cases), ecchymosis with epistaxis (2 cases), melena and renal failure (2 cases), and hematuria (1 case). Patients were given rifampicin and doxycycline along with supportive hematological therapy. All were treated successfully with no evidence of recurrence at follow-up visits. CONCLUSION: Since brucellosis is endemic in developing countries, it must be considered in the differential diagnosis of cases that present with severe thrombocytopenia and hemorrhagic diathesis. |
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Authors:
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Hasan Karsen; Fazilet Duygu; Kubilay Yapıcı; Ali İrfan Baran; Huseyin Taskıran; Irfan Binici |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Archives of Iranian medicine Volume: 15 ISSN: 1029-2977 ISO Abbreviation: Arch Iran Med Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-04-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100889644 Medline TA: Arch Iran Med Country: Iran |
Other Details:
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Languages: eng Pagination: 303-6 Citation Subset: IM |
Affiliation:
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Harran University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Sanliurfa, Turkey. hasankarsen@hotmail.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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