Document Detail


Severe pulmonary toxicity associated with fludarabine and possible contribution of rituximab.
MedLine Citation:
PMID:  20357439     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fludarabine is a nucleoside analogue used in the treatment of low-grade lymphoproliferative disorders and in conditioning regimens of non-myeloablative allogeneic stem cell transplantation. This is a relatively safe drug for clinical use but may cause side effects, some of which may be life-threatening. Here a case of severe pulmonary toxicity associated with fludarabine and a possible contribution of rituximab is presented and the literature reviewed.
Authors:
U Disel; S Paydas; S Yavuz; E Karakoc
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-03-30
Journal Detail:
Title:  Chemotherapy     Volume:  56     ISSN:  1421-9794     ISO Abbreviation:  Chemotherapy     Publication Date:  2010  
Date Detail:
Created Date:  2010-05-10     Completed Date:  2010-08-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0144731     Medline TA:  Chemotherapy     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  89-93     Citation Subset:  IM    
Copyright Information:
(c) 2010 S. Karger AG, Basel.
Affiliation:
Department of Oncology and Intensive Care Unit, Cukurova University Faculty of Medicine, Adana, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Antibodies, Monoclonal / administration & dosage
Antineoplastic Combined Chemotherapy Protocols / adverse effects*,  therapeutic use
Humans
Lung Diseases / chemically induced*,  physiopathology
Lymphoma, Follicular / drug therapy
Male
Middle Aged
Severity of Illness Index
Vidarabine / administration & dosage,  analogs & derivatives
Chemical
Reg. No./Substance:
0/Antibodies, Monoclonal; 0/rituximab; 21679-14-1/fludarabine; 5536-17-4/Vidarabine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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