Document Detail


Severe Mycoplasma pneumoniae-associated mucositis treated with immunoglobulins.
MedLine Citation:
PMID:  21535132     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Mycoplasma pneumoniae-associated mucositis (MPAM), previously labeled as atypical Stevens-Johnson syndrome (SJS), SJS with minimal or no skin manifestations, is a rare non-respiratory manifestation of Mycoplasma pneumoniae infection. The nineteen cases described so far in children and young adults were characterized by a high male gender prevalence (16/19) and a good response to appropriate antibiotic treatment and supportive care in the majority of patients. We describe a case of MPAM in a previously healthy girl, who improved after a 0.5 g/kg daily dose of intravenous immunoglobulins (IVIG) for 4 consecutive days, after traditional therapy had failed. CONCLUSION: The successful treatment with intravenous immunoglobulins described in the present report suggests that, where appropriate antibiotic and supportive therapy fails to improve the clinical course of severe Mycoplasma pneumoniae-associated mucositis, IVIG treatment is worth considering.
Authors:
Silvia Bressan; Teresa Mion; Barbara Andreola; Gianni Bisogno; Liviana Da Dalt
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-5-2
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  -     ISSN:  1651-2227     ISO Abbreviation:  -     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-5-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Acta Paediatrica © 2011 Foundation Acta Paediatrica.
Affiliation:
Department of Pediatrics -University of Padova - Padova, Italy.
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