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Severe Diarrhea Following Neurolytic Coeliac Plexus Block: Case Report and Literature Review.
MedLine Citation:
PMID:  21422068     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Diarrhea is one of the commonest complication following coeliac plexus ablative procedures. It is believed to occur due to inadvertent chemical sympathectomy by the block. For the majority of patients, complications are temporary and self limited. Unfortunately few cases of refractory diarrhea have been reported and some of them proved fatal. The mainstay of therapy is aggressive hydration to restore body fluids and early treatment with antidiarrheal agents. This includes the use of high fiber diet, opioids, anticholinergics, alpha 2 agonists and somatostatin analogues e.g., Octreotide in an attempt to inhibit gut motility and control the diarrhea. We would like to present a case of severe diarrhea following a neurolytic coeliac plexus block using alcohol 50% in a patient with cancer pancreas. Patient achieved a significant reduction in her pain scores but developed severe diarrhea and dehydration. Diarrhea was refractory to medical treatment and patient died few weeks later.
Authors:
Mohamed El Toukhy; Nicholas Ta Campkin
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-21
Journal Detail:
Title:  The American journal of hospice & palliative care     Volume:  -     ISSN:  1938-2715     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9008229     Medline TA:  Am J Hosp Palliat Care     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Queen Alexandra Hospital, Portsmouth Hospitals NHS Trust, Portsmouth, UK.
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