| Severe cutaneous adverse reactions: acute generalized exanthematous pustulosis, toxic epidermal necrolysis and Stevens-Johnson syndrome. | |
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MedLine Citation:
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PMID: 20609860 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Most drug hypersensitivity reactions show skin symptoms. The most severe cutaneous manifestations include pustular and bullous skin eruptions. These 2 manifestations can lead to acute generalized exanthematous pustulosis or Stevens-Johnson syndrome and toxic epidermal necrolysis. These complications are rare, but should be known to any doctor prescribing drugs because they are life threatening and early stoppage of treatment is mandatory. |
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Authors:
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Thomas Harr; Lars E French |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: The Medical clinics of North America Volume: 94 ISSN: 1557-9859 ISO Abbreviation: Med. Clin. North Am. Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-08 Completed Date: 2010-09-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2985236R Medline TA: Med Clin North Am Country: United States |
Other Details:
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Languages: eng Pagination: 727-42, x Citation Subset: AIM; IM |
Copyright Information:
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Copyright (c) 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Dermatology, University Hospital Zurich, Gloriastrasse 31, Zurich 8031, Switzerland. thomas.harr@usz.ch |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Generalized Exanthematous Pustulosis
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chemically induced*,
diagnosis Diagnosis, Differential Epidermal Necrolysis, Toxic / diagnosis*, drug therapy, etiology Humans Immunoglobulins, Intravenous / therapeutic use Immunologic Factors / therapeutic use Pharmaceutical Preparations / adverse effects Prescription Drugs / adverse effects* Prognosis Risk Factors Stevens-Johnson Syndrome / chemically induced*, diagnosis, drug therapy |
| Chemical | |
Reg. No./Substance:
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0/Immunoglobulins, Intravenous; 0/Immunologic Factors; 0/Pharmaceutical Preparations; 0/Prescription Drugs |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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