| Seton drainage and fibrin glue injection for complex anal fistulas. | |
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MedLine Citation:
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PMID: 19210300 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The study aimed to evaluate the efficacy of fibrin glue in the treatment of complex anal fistula. METHOD: Thirty consecutive patients with a complex anal fistula underwent glue instillation after an 8 week period of seton drainage. Cure was defined as complete closure of any secondary opening, absence of fistula seepage, and no abscess formation. RESULTS: The mean age of the patients (15 males) was 40.5 (range, 22.8-69.1) years. The mean duration of follow-up was 11.7 (range, 0.2-33.5) months. Complete closure of the fistula was achieved in 17 patients at 1 month but in two patients a delayed abscess occurred. At the end of follow-up, 15 (50%) patients were considered to have been cured. The success rate was no different in cases of Crohn's disease or when postoperative antibiotic therapy was given. There was, however, a significant difference in success following regional vs general anaesthesia (68.4 vs 18.2% success, P = 0.02). CONCLUSION: Fibrin glue cured 50% of our first 30 patients, and regional anaesthesia was predictive of success. |
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Authors:
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V de Parades; H Safa Far; I Etienney; J-D Zeitoun; P Atienza; P Bauer |
Publication Detail:
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Type: Journal Article Date: 2009-02-07 |
Journal Detail:
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Title: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland Volume: 12 ISSN: 1463-1318 ISO Abbreviation: Colorectal Dis Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-05-07 Completed Date: 2010-08-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100883611 Medline TA: Colorectal Dis Country: England |
Other Details:
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Languages: eng Pagination: 459-63 Citation Subset: IM |
Affiliation:
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Proctologie médico-interventionnelle Groupe hospitalier Diaconesses - Croix Saint Simon, rue du Sergent Bauchat, Paris, France. proctologie@hopital-dcss.org |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Combined Modality Therapy Drainage Female Fibrin Tissue Adhesive / administration & dosage* Humans Male Middle Aged Prospective Studies Rectal Fistula / surgery, therapy* Tissue Adhesives / administration & dosage* Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Fibrin Tissue Adhesive; 0/Tissue Adhesives |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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