| Sesquiterpene lactones from Smyrnium olusatrum. | |
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MedLine Citation:
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PMID: 11454342 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Fruits of Smyrnium olusatrum afforded three sesquiterpene lactones, namely, 1beta,8beta-dihydroxyeudesman-3,7(11)-dien-8alpha,12-olide, 1beta,8beta-dihydroxyeudesman-4(15),7(11)-dien-8alpha,l2-olide, and 1beta,10alpha,4alpha,5beta-diepoxy-6beta-hydroxyglechoman-8alpha,12-olide. Four related known sesquiterpenes were also isolated and characterized. The structure elucidation of the isolated compounds was based primarily on 1D and 2D NMR analyses. The in vitro cytotoxicity of the extract and isolated compounds against P-388 mouse lymphoma cells will be also discussed. |
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Authors:
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A A El-Gamal |
Publication Detail:
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Type: In Vitro; Journal Article |
Journal Detail:
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Title: Phytochemistry Volume: 57 ISSN: 0031-9422 ISO Abbreviation: Phytochemistry Publication Date: 2001 Aug |
Date Detail:
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Created Date: 2001-07-16 Completed Date: 2001-10-18 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0151434 Medline TA: Phytochemistry Country: United States |
Other Details:
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Languages: eng Pagination: 1197-200 Citation Subset: IM |
Affiliation:
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Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, 35516, Mansoura, Egypt. aelgama100@yahoo.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antineoplastic Agents, Phytogenic / isolation & purification, pharmacology Chromatography Drug Screening Assays, Antitumor Fruit / chemistry Lactones / isolation & purification*, pharmacology Libya Magnetic Resonance Spectroscopy Mice Plant Extracts / chemistry, pharmacology Plants, Medicinal / chemistry* Sesquiterpenes / isolation & purification*, pharmacology Sesquiterpenes, Eudesmane* Spectrophotometry, Infrared Tumor Cells, Cultured |
| Chemical | |
Reg. No./Substance:
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0/1,10,4,5-diepoxy-6-hydroxyglechoman-8,12-olide; 0/1,8-dihydroxyeudesman-3,7(11)-dien-8,12-olide; 0/1beta,8beta-dihydroxy-eudesman-4(15),7(11)-dien-8alpha,l2-olide; 0/Antineoplastic Agents, Phytogenic; 0/Lactones; 0/Plant Extracts; 0/Sesquiterpenes; 0/Sesquiterpenes, Eudesmane |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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