| Sesquiterpene lactone dermatitis. Cross-sensitivity in costus-sensitized patients. | |
| | |
MedLine Citation:
|
PMID: 7352764 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Thirteen costus-sensitive patients were patch tested with 38 sesquiterpene lactones of five different classes over a two-year period. Cross-reacting agents fell into two chemical categories: (1) those that resembled the primary sensitizer, and (2) those belonging to different skeletal classes. An exocyclic methylene group conjugated to a gamma-lactone was present in both chemicals that cross-reacted and those that did not. The difference between these two groups is that cross-reacting chemicals are not highly substituted, tending to be lipophilic, while those giving negative responses all are highly substituted at the C-8/C-6 position. This functional group may hinder binding of exocyclic methylene with skin protein or the actual antigenic site with an immune receptor cell. |
| | |
Authors:
|
W L Epstein; G W Reynolds; E Rodriguez |
Related Documents
:
|
22263424 - Annual variations of odor concentrations and emissions from swine gestation, farrowing,... 22471734 - Rapid environmental degradation in a subarctic ecosystem influences resource use of a k... 11720074 - Skin benefits from continuous topical administration of a zinc oxide/petrolatum formula... 22716964 - The helminth community of geophagus proximus (perciformes: cichlidae) from a tributary ... 19005804 - Polycyclic aromatic hydrocarbons in crude oil-contaminated soil: a two-step method for ... 23509944 - Meristem temperature substantially deviates from air temperature even in moderate envir... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Archives of dermatology Volume: 116 ISSN: 0003-987X ISO Abbreviation: Arch Dermatol Publication Date: 1980 Jan |
Date Detail:
|
Created Date: 1980-03-27 Completed Date: 1980-03-27 Revised Date: 2008-03-17 |
Medline Journal Info:
|
Nlm Unique ID: 0372433 Medline TA: Arch Dermatol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 59-60 Citation Subset: AIM; IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Cross Reactions* Dermatitis, Contact / etiology*, immunology Humans Lactones / adverse effects Patch Tests Perfume / adverse effects* Plant Extracts / adverse effects Sesquiterpenes / adverse effects |
| Chemical | |
Reg. No./Substance:
|
0/Lactones; 0/Perfume; 0/Plant Extracts; 0/Sesquiterpenes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Porphyria turcica. Twenty years after hexachlorobenzene intoxication.
Next Document: Sebaceous neoplasms associated with visceral carcinomas.