Document Detail

Serum tryptase in idiopathic anaphylaxis: a case report and review of the literature.
MedLine Citation:
PMID:  8010539     Owner:  NLM     Status:  MEDLINE    
Anaphylaxis is a life-threatening disease that characteristically presents with multiple arrays of dermatologic, respiratory, cardiovascular, and gastrointestinal derangements, in general, suddenly after exposure to an allergen. It can, however, occur without an identifiable precipitant or event, and this well-defined entity has been called idiopathic anaphylaxis. The diagnosis of idiopathic anaphylaxis is made after an appropriate allergic evaluation and exclusion of a provocative trigger. We report an unusual case of manifesting with gastroenteritis, urticaria, hypotension, and syncope. Measurement of serum tryptase, a mast cell enzyme, was used to substantiate the diagnosis. Tryptase level is a useful test that can be used to help diagnose this potentially fatal disease.
T Tanus; D Mines; P C Atkins; A I Levinson
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Annals of emergency medicine     Volume:  24     ISSN:  0196-0644     ISO Abbreviation:  Ann Emerg Med     Publication Date:  1994 Jul 
Date Detail:
Created Date:  1994-07-19     Completed Date:  1994-07-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8002646     Medline TA:  Ann Emerg Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  104-7     Citation Subset:  AIM; IM    
Department of Medicine, University of Pennsylvania, Philadelphia.
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MeSH Terms
Anaphylaxis / diagnosis*,  etiology,  immunology
Serine Endopeptidases / blood*
Reg. No./Substance:
EC 3.4.21.-/Serine Endopeptidases; EC 3.4.21.-/chymase 2; EC; EC

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