| Serum total and free thyroxine and triiodothyronine during dynamic muscular exercise in man. | |
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MedLine Citation:
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PMID: 407805 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effect of strenuous dynamic muscular exercise on serum-free thyroxine (FT4) and free triiodothyronine (FT3) concentrations has been studied in 10 healthy subjects. In the course of 7.8-19 min of treadmill exercise (protocol of R. A. Bruce), the group showed a mean increase in serum albumin concentration of 11.4% (P less than 0.01). Five subjects demonstrated an increase in FT4 concentrations (x = +54%) and five showed decreased FT4 (x = -36%). The difference in FT4 concentrations was accounted for primarily by acute alterations in dialyzable fraction T4 (DFT4) rather than total serum T4. Mean changes in DFT4 were statistically significant (P less than 0.02) when increased FT4 and decreased FT4 groups were compared. Acute exercise was accompanied by a 9% decrease in dialyzable fraction T3 (DFT3) (P less than 0.02) in the 10 subjects, but the concomitant decrease in FT3 concentration was not significant. Changes in DFT4 and DFT3 and FT4 and FT3 concentrations were not correlated. Trends in double product (heart rate times blood pressure) with maximal exercise and in double-product recovery after exercise suggested that increased FT4 concentrations developed in subjects who were physically better trained. |
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Authors:
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D G Caralis; L Edwards; P J Davis |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The American journal of physiology Volume: 233 ISSN: 0002-9513 ISO Abbreviation: Am. J. Physiol. Publication Date: 1977 Aug |
Date Detail:
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Created Date: 1977-09-29 Completed Date: 1977-09-29 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0370511 Medline TA: Am J Physiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: E115-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Pressure Female Heart Rate Humans Male Oxygen Consumption Physical Exertion* Serum Albumin Thyroxine / blood* Thyroxine-Binding Proteins Triiodothyronine / blood* |
| Chemical | |
Reg. No./Substance:
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0/Serum Albumin; 0/Thyroxine-Binding Proteins; 6893-02-3/Triiodothyronine; 7488-70-2/Thyroxine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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