Document Detail


Serum total free radical trapping ability in acute myocardial infarction.
MedLine Citation:
PMID:  1760883     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Serum total free radical trapping abilities (TRAP experimental) were measured in 15 patients with acute myocardial infarction (AMI) and compared to sex- and age-matched controls. TRAP experimental values were significantly lower (p less than 0.01) in the AMI group. Theoretical trapping abilities were also calculated and compared with experimentally derived values. In the AMI group there was no significant difference between the experimental and calculated TRAP, but in the control group experimental values were significantly higher (p less than 0.01) than calculated values. In the control group regression analysis revealed that alpha-tocopherol and ascorbate taken together most closely explained the radical trapping ability of sera, with a regression equation: TRAP experimental = 562.9 + 2.082 (alpha-tocopherol + ascorbate). In the AMI group no relationship between the serum antioxidants and TRAP experimental was observed.
Authors:
C W Mulholland; J J Strain
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical biochemistry     Volume:  24     ISSN:  0009-9120     ISO Abbreviation:  Clin. Biochem.     Publication Date:  1991 Oct 
Date Detail:
Created Date:  1992-02-11     Completed Date:  1992-02-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0133660     Medline TA:  Clin Biochem     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  437-41     Citation Subset:  IM    
Affiliation:
Biomedical Science Research Centre, University of Ulster, Northern Ireland, Great Britain.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adult
Aged
Aged, 80 and over
Antioxidants / metabolism
Female
Free Radicals / blood*
Humans
Male
Methods
Middle Aged
Myocardial Infarction / blood*
Oxygen / blood
Regression Analysis
Chemical
Reg. No./Substance:
0/Antioxidants; 0/Free Radicals; 7782-44-7/Oxygen

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