Document Detail

Serum sickness with acquired precipitating antibodies during rush immunotherapy (2 cases).
MedLine Citation:
PMID:  3137849     Owner:  NLM     Status:  MEDLINE    
Serum sickness can be induced by several heterologous proteins. Two patients undergoing rush immunotherapy developed clinical symptoms of serum sickness. One patient received a mite and grass pollens mixture and the second patient a wasp and yellow-jacket venoms mixture. Precipitating antibodies against some allergens used for immunotherapy were found in their serum during the disease but not in the sera drawn before immunotherapy and two and three months after. Pathologic findings showed a leukocytoclastic vasculitis. Pathogenesis of this complication is discussed.
M H Chabane; F Leynadier; G M Halpern; J Dry
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of allergy     Volume:  61     ISSN:  0003-4738     ISO Abbreviation:  Ann Allergy     Publication Date:  1988 Sep 
Date Detail:
Created Date:  1988-10-12     Completed Date:  1988-10-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372346     Medline TA:  Ann Allergy     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  216-9     Citation Subset:  IM    
Centre D'Allergie, Hopital Rothschild, Paris, France.
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MeSH Terms
Antibodies / analysis*
Immunotherapy / adverse effects*,  methods
Middle Aged
Serum Sickness / etiology*,  immunology,  pathology
Skin / pathology
Time Factors
Reg. No./Substance:

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