Document Detail

Serum sialic acid and ceruloplasmin levels in experimental fluorosis.
MedLine Citation:
PMID:  6836584     Owner:  NLM     Status:  MEDLINE    
The present study describes the effect of fluoride (10 mg NaF/kg body weight/day) on the total protein-bound sialic acid and ceruloplasmin levels in rabbit serum after receiving sodium fluoride intragastrically for 3, 5, 8 and 10 months. The total protein-bound sialic acid and ceruloplasmin levels in serum were reduced, whereas the fluoride levels were increased showing a cumulative effect. It is suggested that the decreased circulatory sialic acid and ceruloplasmin levels with increased serum fluoride may be used in an early detection of fluorosis.
Y D Sharma
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Toxicology letters     Volume:  15     ISSN:  0378-4274     ISO Abbreviation:  Toxicol. Lett.     Publication Date:  1983 Jan 
Date Detail:
Created Date:  1983-05-05     Completed Date:  1983-05-05     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7709027     Medline TA:  Toxicol Lett     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  1-5     Citation Subset:  IM    
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MeSH Terms
Ceruloplasmin / analysis*
Fluoride Poisoning*
Sialic Acids / blood*
Sodium Fluoride / poisoning*
Time Factors
Reg. No./Substance:
0/Sialic Acids; 7681-49-4/Sodium Fluoride; EC

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