| Serum resistin in persistent allergic rhinitis: preliminary data in adults. | |
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MedLine Citation:
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PMID: 20093199 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Adipokines may exert pro-inflammatory activities in allergic rhinitis. Resistin is a new adipokine. Only one study reported that resistin may be involved in allergic rhinitis. However, that study was conducted in children. Therefore, the present study aimed at confirming these findings also in adult patients with persistent allergic rhinitis (PER). METHODS: The study included 85 PER patients subjects 25 (11 males, mean age 35.4 years) with mild symptoms and 60 (27 males, mean age 36.8 years) with moderate-severe ones. All subjects were consecutively evaluated. A skin prick test and blood sampling for assessing serum resistin levels were performed in all subjects. RESULTS: Patients with moderate-severe symptoms had higher resistin levels than mild ones (p=0.02). CONCLUSION: This study provides the preliminary evidence that resistin serum levels depend on symptom severity also in adults with PER. |
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Authors:
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Giorgio Ciprandi; Mara De Amici; Maria Angela Tosca; Gianluigi Marseglia |
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Publication Detail:
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Type: Journal Article Date: 2010-01-18 |
Journal Detail:
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Title: International immunopharmacology Volume: 10 ISSN: 1878-1705 ISO Abbreviation: Int. Immunopharmacol. Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-02-26 Completed Date: 2010-06-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100965259 Medline TA: Int Immunopharmacol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 371-2 Citation Subset: IM |
Copyright Information:
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Copyright 2010 Elsevier B.V. All rights reserved. |
Affiliation:
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Department of Internal Medicine, Azienda Ospedaliera Universitaria San Martino, University of Genoa, Genoa, Italy. gio.cip@libero.it |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adipokines
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blood Adult Female Humans Immunoassay Male Resistin / blood* Rhinitis, Allergic, Perennial / blood* Skin Tests |
| Chemical | |
Reg. No./Substance:
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0/Adipokines; 0/Resistin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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