Document Detail

Serum relaxin levels in prostaglandin E2 induced abortions.
MedLine Citation:
PMID:  748978     Owner:  NLM     Status:  MEDLINE    
Relaxin, a peptide hormone produced only by the corpus luteum of pregnancy, can be used as a marker of luteal function in human pregnancy. Serum immunoreactive relaxin levels were measured serially in six women having second trimester abortions induced with intravaginal prostaglandin E2 (PGE2) suppositories. All patients aborted within 17 hours of the first suppository. No significant changes were detectable in serum relaxin levels in any of the patients. It is concluded that PGE2 does not interfere with the corpus luteum's ability to secrete relaxin in the second trimester of human pregnancy.
J Quagliarello; L Cederqvist; B Steinetz; G Weiss
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Prostaglandins     Volume:  16     ISSN:  0090-6980     ISO Abbreviation:  Prostaglandins     Publication Date:  1978 Dec 
Date Detail:
Created Date:  1979-06-26     Completed Date:  1979-06-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0320271     Medline TA:  Prostaglandins     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1003-6     Citation Subset:  IM    
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MeSH Terms
Abortion, Induced*
Corpus Luteum / secretion
Pregnancy Trimester, Second
Prostaglandins E, Synthetic* / administration & dosage,  therapeutic use
Relaxin / blood*,  secretion
Reg. No./Substance:
0/Prostaglandins E, Synthetic; 0/Suppositories; 9002-69-1/Relaxin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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