Document Detail

Serum proteins in guinea-pigs and horses infected with Trypanosoma evansi (Steel, 1885).
MedLine Citation:
PMID:  2399649     Owner:  NLM     Status:  MEDLINE    
The serum protein pattern in guinea-pigs infected with T. evansi was analysed and compared with those found in horses with either a natural or experimental infection. In both species, a highly significant decrease in albumin levels and an increase in gamma-globulins were seen, leading to a very low albumin/globulin ratio. No significant differences in total protein levels between healthy and infected animals were registered. Likewise, alpha-globulins were not significantly affected. A decrease in beta-globulins was observed in one horse and in guinea-pigs with experimental infection, while in horses with natural infections this decrease was not constant. The serum protein patterns in guinea-pigs infected with T. evansi appeared similar to those occurring in horses infected with this parasite. Guinea-pigs, therefore may be useful laboratory models for the study of equine trypanosomosis caused by T. evansi.
C M Monzón; V I Villavicencio
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Veterinary parasitology     Volume:  36     ISSN:  0304-4017     ISO Abbreviation:  Vet. Parasitol.     Publication Date:  1990 Jul 
Date Detail:
Created Date:  1990-10-16     Completed Date:  1990-10-16     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7602745     Medline TA:  Vet Parasitol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  295-301     Citation Subset:  IM    
Veterinary Diagnostic and Research Centre-CEDIVEF, Formosa, Argentina.
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MeSH Terms
Blood Protein Electrophoresis / veterinary
Blood Proteins / analysis*
Disease Models, Animal
Guinea Pigs
Horse Diseases / blood*
Trypanosomiasis / blood,  veterinary*
Reg. No./Substance:
0/Blood Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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