Document Detail

Serum protein analysis and bone marrow cytology in patients with an extreme elevation of the erythrocyte sedimentation rate.
MedLine Citation:
PMID:  644295     Owner:  NLM     Status:  MEDLINE    
One hundred patients in whom an Erythrocyte Sedimentation Rate (ESR) in excess of 100 mm. in the first hour was found on 2 consecutive occasions were investigated. Serum protein electrophoresis was performed on 96 of these patients and bone marrow examination on 55 patients. Acute infection was the commonest diagnosis though the majority of patients had 2 or more separate conditions each contributing to the elevation of the ESR. Quantitive serum protein electrophoresis was abnormal in all but one patient and was of limited diagnostic value. A definite band in the globulin region was detected in 11 patients, 7 of whom were found to have myelomatosis. Bone marrow examination was useful only in patients with a discrete band in the globulin fraction or with a specific haematological abnormality. It is suggested, therefore, that bone marrow examination be confined to patients with such abnormalities irrespective of an elevation of their ESR.
M J Ford; F M Parrish; J A Innes; R G Webber; N C Allan; D B Horn; J F Munro
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Scottish medical journal     Volume:  23     ISSN:  0036-9330     ISO Abbreviation:  Scott Med J     Publication Date:  1978 Apr 
Date Detail:
Created Date:  1978-06-17     Completed Date:  1978-06-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2983335R     Medline TA:  Scott Med J     Country:  SCOTLAND    
Other Details:
Languages:  eng     Pagination:  131-4     Citation Subset:  IM    
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MeSH Terms
Blood Protein Electrophoresis
Blood Proteins / analysis*
Blood Sedimentation*
Bone Marrow / pathology*
Bone Marrow Examination
Middle Aged
Reg. No./Substance:
0/Blood Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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