Document Detail

Serum prostate specific antigen levels in non-specific granulomatous prostatitis.
MedLine Citation:
PMID:  8814847     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate serum prostate-specific antigen (PSA) levels in patients with granulomatous prostatitis, an inflammatory condition that can clinically mimic malignancy. PATIENTS AND METHODS: The study comprised 10 consecutive patients (age range 53-80 years) with histologically-documented granulomatous prostatitis and who had serum PSA levels recorded before and after diagnosis. RESULTS: PSA levels in six of the patients were normal (< 4.0 ng/mL) at diagnosis. The other four had slightly elevated PSA levels, with three being between 4.0 and 6.0 ng/mL and the other 10.1 ng/mL. In six of the patients, there was a dramatic decrease (> 40%) in PSA level within 6-12 months after the histological documentation of granulomatous prostatitis. At the final follow-up, all 10 patients had normal PSA levels. CONCLUSION: Granulomatous prostatitis may cause a relatively mild and transient increase in serum PSA level which resolves when the inflammation subsides.
V O Speights; P N Brawn
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of urology     Volume:  77     ISSN:  0007-1331     ISO Abbreviation:  Br J Urol     Publication Date:  1996 Mar 
Date Detail:
Created Date:  1996-10-10     Completed Date:  1996-10-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  15740090R     Medline TA:  Br J Urol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  408-10     Citation Subset:  IM    
Department of Pathology, Texas A&M University Health Science Center College of Medicine, Temple, USA.
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MeSH Terms
Aged, 80 and over
Granuloma / blood*,  diagnosis
Middle Aged
Prostate-Specific Antigen / blood*
Prostatitis / blood*,  diagnosis
Reg. No./Substance:
EC Antigen

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