Document Detail

Serum prolactin and oestradiol levels in women with cyclical mastalgia.
MedLine Citation:
PMID:  7319468     Owner:  NLM     Status:  MEDLINE    
Basal serum prolactin and serum oestradiol-17-beta concentrations were measured four times during one menstrual cycle in 20 women with severe cyclical mastalgia and normal to slightly fibroadenotic breasts. A group of 10 normal women who had never experienced mastalgia served as controls. Basal serum prolactin was significantly elevated in patients compared to normals, although within the normal range. Serum oestradiol concentrations did not differ in the two groups and were also within the normal range. A significant positive correlation between oestradiol and prolactin was found in patients and normals, but with larger prolactin levels in patients. The results point towards a prolactin secretory hypersensitivity for oestradiol in patients with cyclical mastalgia. Prolactin is considered a central factor in the eliciting of cyclical mastalgia.
S Watt-Boolsen; A N Andersen; M Blichert-Toft
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme     Volume:  13     ISSN:  0018-5043     ISO Abbreviation:  Horm. Metab. Res.     Publication Date:  1981 Dec 
Date Detail:
Created Date:  1982-03-22     Completed Date:  1982-03-22     Revised Date:  2009-02-19    
Medline Journal Info:
Nlm Unique ID:  0177722     Medline TA:  Horm Metab Res     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  700-2     Citation Subset:  IM    
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MeSH Terms
Estradiol / blood*
Fibrocystic Breast Disease / blood
Middle Aged
Pain / blood*
Prolactin / blood*
Reg. No./Substance:
50-28-2/Estradiol; 9002-62-4/Prolactin

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