| Serum phospholipid fractions measured by two dimensional thin layer chromatography in normal pregnancy. | |
MedLine Citation:
|
PMID: 2628299 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Serum phospholipid fractions were quantitated by two dimensional thin layer chromatography in 85 apparently normal pregnant women at different gestational period. Fifteen healthy non-pregnant women matched for age served as controls. Normal chromatogram showed eight spots of serum phospholipid viz., phosphatidic acid (PA, 3.9 +/- 0.5%), cardiolipin (C, 7.2 +/- 0.4%), phosphatidylethanolamine (PE, 10.6 +/- 1.1%), phosphatidylglycerol (PG, 3.2 +/- 0.6%), lecithin (L, 34.5 +/- 1.8%), sphingomyelin (S, 31.0 +/- 1.4%), lysolecithin (LL, 8.6 +/- 1.2%) and phosphalidylionositol (PI, 1.0 +/- 0.2%). Serum total phospholipid which increased with gestational age, being lowest at 6 wk (220.2 +/- 4.8 mg/dl) and highest at 38 wk (290.3 +/- 4.5 mg/dl), started declining at term (275.8 +/- 5.8 mg/dl) and returned to levels in normal nonpregnant women (214.1 +/- 4.7 mg/dl) at 4 wk after delivery (217.2 +/- 3.3 mg/dl). PG was absent in both the first and second trimester and first appeared between 31-32 wk, i.e., in the third trimester of pregnancy when the mean per cent of PG was 0.7 +/- 0.4 per cent. During the first trimester when the L/S ratio was less than 1.2 the PI level was low (0.8 +/- 0.2%). Parallel to the increase in the L/S ratio to 2.0, the content of PI increased to 2.6 +/- 0.4 per cent. PG first appeared (0.7 +/- 0.4%) and PI concomitantly decreased (2.1 +/- 0.3%) when the L/S ratio exceeded 2.0 at 31-32 wk. Sequential analysis of maternal serum phospholipid fractions may be used as an additional tool in predicting gestational age of normal growing pregnancy. |
Authors:
|
S K Batabyal; S Chaudhuri; A Ghosh; B Mitra; C S Dawn |
Related Documents
:
|
6489849 - Calcium, parathyroid hormone and calcitonin in normal pregnancy and preeclampsia. 12456629 - Vascular endothelial growth factor (vegf) and discrimination between abnormal intrauter... 2697189 - Ca-125 ovarian cancer associated antigen in cancer and pregnancy: interpretation of enz... 15694969 - Serum and placental interleukin-18 are elevated in preeclampsia. 1772259 - Depressed serum erythropoietin in pregnant women with elevated blood lead. 6974239 - Heterogeneity of pregnancy-specific beta 1-glycoprotein following purification from mat... 15290969 - Free-stall dimensions: effects on preference and stall usage. 22614129 - Fetal cardiac function: technical considerations and potential research and clinical ap... 22791759 - A case of nondiabetic ketoacidosis in third term twin pregnancy. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: The Indian journal of medical research Volume: 90 ISSN: 0971-5916 ISO Abbreviation: Indian J. Med. Res. Publication Date: 1989 Oct |
Date Detail:
|
Created Date: 1990-04-23 Completed Date: 1990-04-23 Revised Date: 2013-04-18 |
Medline Journal Info:
|
Nlm Unique ID: 0374701 Medline TA: Indian J Med Res Country: INDIA |
Other Details:
|
Languages: eng Pagination: 315-9 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Chromatography, Thin Layer Female Humans Phospholipids / blood* Pregnancy / blood* |
| Chemical | |
Reg. No./Substance:
|
0/Phospholipids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Anopheline fauna of Koraput district, Orissa state, with particular reference to transmission of mal...
Next Document: Influence of malnutrition on social maturity, visual motor coordination & memory in rural school chi...