| Serum phospholipase A in hospitalized patients. | |
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MedLine Citation:
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PMID: 2766556 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Threehundred and thirty sera from hospitalized patients were analyzed for phospholipase A (PLA) activity. About 30% of unselected patients showed values above the normal range (0 to 10 U/l). The ratio of pathological to normal results was even higher in intensive care patients (around 1:1) and in patients with severe infections (2:1). 'Hyperphospholipasemia' was not typical for any defined organ system. From an etiological viewpoint, infectious diseases were most often related to increased PLA, followed by myocardial infarction and insufficiency and by malignant diseases. It is suggested that phospholipase A is a marker enzyme for the phagocytic activity in inflammation and necrosis. |
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Authors:
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G E Hoffmann; R Hiefinger; B Steinbrueckner |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinica chimica acta; international journal of clinical chemistry Volume: 183 ISSN: 0009-8981 ISO Abbreviation: Clin. Chim. Acta Publication Date: 1989 Jul |
Date Detail:
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Created Date: 1989-10-06 Completed Date: 1989-10-06 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 1302422 Medline TA: Clin Chim Acta Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 59-64 Citation Subset: IM |
Affiliation:
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Institute of Clinical Chemistry, Bogenhausen Hospital, Munich, FRG. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Bacterial Infections
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enzymology Critical Care Female Humans Infection / enzymology* Leukocyte Count Male Organ Specificity Phospholipases / blood* Phospholipases A / blood* Photometry Reference Values |
| Chemical | |
Reg. No./Substance:
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EC 3.1.-/Phospholipases; EC 3.1.1.-/Phospholipases A |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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