Document Detail

Serum phospholipase A in hospitalized patients.
MedLine Citation:
PMID:  2766556     Owner:  NLM     Status:  MEDLINE    
Threehundred and thirty sera from hospitalized patients were analyzed for phospholipase A (PLA) activity. About 30% of unselected patients showed values above the normal range (0 to 10 U/l). The ratio of pathological to normal results was even higher in intensive care patients (around 1:1) and in patients with severe infections (2:1). 'Hyperphospholipasemia' was not typical for any defined organ system. From an etiological viewpoint, infectious diseases were most often related to increased PLA, followed by myocardial infarction and insufficiency and by malignant diseases. It is suggested that phospholipase A is a marker enzyme for the phagocytic activity in inflammation and necrosis.
G E Hoffmann; R Hiefinger; B Steinbrueckner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinica chimica acta; international journal of clinical chemistry     Volume:  183     ISSN:  0009-8981     ISO Abbreviation:  Clin. Chim. Acta     Publication Date:  1989 Jul 
Date Detail:
Created Date:  1989-10-06     Completed Date:  1989-10-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1302422     Medline TA:  Clin Chim Acta     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  59-64     Citation Subset:  IM    
Institute of Clinical Chemistry, Bogenhausen Hospital, Munich, FRG.
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MeSH Terms
Bacterial Infections / enzymology
Critical Care
Infection / enzymology*
Leukocyte Count
Organ Specificity
Phospholipases / blood*
Phospholipases A / blood*
Reference Values
Reg. No./Substance:
EC 3.1.-/Phospholipases; EC 3.1.1.-/Phospholipases A

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