Document Detail

Serum pattern of thyroxine (T4), 3,3',5-triiodothyronine (T3) and 3,3',5'-triiodothyronine (rT3) in fed and fasted cocks following TRH stimulation.
MedLine Citation:
PMID:  1950229     Owner:  NLM     Status:  MEDLINE    
Food deprivation for 27 and 75h in cocks decreased serum levels of T3 maximally by 61.1% and increased the level of rT3 by 51.4% and that of T4 by 22.4%. Injection of a single dose of TRH (10 micrograms/kg b.w.) increased serum levels of all 3 iodothyronines in both fed and food-deprived animals. In fasted, TRH-treated birds the peak of serum rT3 was 80.5 and 73.3% above control levels in 27- and 75-hr food-deprived cocks, respectively (fed birds: 14.6 and 9.7%); the relevant data for T3 were: 78.3 and 40.4% (fed birds: 95.7 and 127.5%); for T4: 30.0 and 27.0% (fed birds: 9.2 and 6.1%). The greater relative increment of serum rT3 than T3 in food-deprived and TRH-treated cocks was supported by a fall of the serum T3/rT3 ratio to 78.7 and 27.9% in fed cocks and 27- and 75-hr fasted animals, respectively. We conclude, that food deprivation modifies the response of the hypophysis-thyroid axis to exogenous TRH in the sense that during fasting the production of rT3 is enhanced relative to T3.
K I Abdel-Fattah; S Bobek; A Sechman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Zentralblatt für Veterinärmedizin. Reihe A     Volume:  38     ISSN:  0514-7158     ISO Abbreviation:  Zentralbl Veterinarmed A     Publication Date:  1991 Jul 
Date Detail:
Created Date:  1991-12-23     Completed Date:  1991-12-23     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0331323     Medline TA:  Zentralbl Veterinarmed A     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  401-8     Citation Subset:  IM    
Department of Animal Physiology, Academy of Agriculture, Kraków, Poland.
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MeSH Terms
Chickens / blood*
Eating / physiology
Food Deprivation / physiology*
Thyroid Gland / physiology
Thyrotropin-Releasing Hormone / pharmacology
Thyroxine / blood*
Triiodothyronine / blood*
Triiodothyronine, Reverse / blood*
Reg. No./Substance:
24305-27-9/Thyrotropin-Releasing Hormone; 5817-39-0/Triiodothyronine, Reverse; 6893-02-3/Triiodothyronine; 7488-70-2/Thyroxine

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