| Serum paraoxonase and arylesterase activities in patients with pulmonary tuberculosis. | |
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MedLine Citation:
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PMID: 21130618 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Background: The aim of the present study was to determine serum paraoxonase and arylesterase activities in tuberculosis, nontuberculosis pulmonary disease and healthy subjects. Materials and methods: In this case-control study we determined the serum paraoxonase and arylesterase activities in 36 patients with pulmonary tuberculosis, 38 nontuberculosis pulmonary disease and 49 healthy controls. Results: The results showed that serum paraoxonase (PON) activity was significantly lower in patients with pulmonary tuberculosis (61.10±51.62IU/L) than healthy controls (98.79±68.79IU/L) (p<0.05). In addition we found that the level of PON activity was significantly lower in patients with nontuberculosis pulmonary disease (67.49±47.88IU/L) than normal individuals (p<0.05). There was no significant differences regarding PON activity between patients with pulmonary tuberculosis and nontuberculosis pulmonary disease (p>0.05). The arylesterase activity was significantly lower in patients with pulmonary tuberculosis than nontuberculosis pulmonary disease and normal subjects (p<0.05). Discussion: The lower paraoxonase and aryesterase activities in pulmonary tuberculosis patients compared to healthy subjects might be due to imbalance of oxidant/antioxidant systems in pulmonary tuberculosis patients which needs more clarification. |
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Authors:
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Mohamamd Naderi; Mohammad Hashemi; Fatemeh Komijani-Bozchaloei; Abdolkarim Moazeni-Roodi; Mohammadamin Momenimoghaddam |
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Publication Detail:
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Type: Journal Article Date: 2010-12-03 |
Journal Detail:
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Title: Pathophysiology : the official journal of the International Society for Pathophysiology / ISP Volume: 18 ISSN: 0928-4680 ISO Abbreviation: Pathophysiology Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-03-04 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9433813 Medline TA: Pathophysiology Country: Netherlands |
Other Details:
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Languages: eng Pagination: 117-20 Citation Subset: - |
Copyright Information:
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Copyright © 2010. Published by Elsevier Ireland Ltd. |
Affiliation:
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Research Center for Infectious Diseases and Tropical Medicine, Zahedan University of Medical Sciences, Zahedan, Iran. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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