| Serum lipoprotein (a) in offspring of patients with premature myocardial infarction. | |
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MedLine Citation:
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PMID: 11467239 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To compare serum Lp(a), lipids: TC, TG and lipoproteins: HDL-C and LDL-C levels of offspring with history of paternal myocardial infarction with the serum levels in offspring without paternal history of myocardial infarction. SETTING: Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre, Karachi. METHODS: Thirty offspring between the ages of 8-25 years with the history of paternal myocardial infarction were randomly selected from population and were matched with offspring having no history of parental myocardial infarction. RESULTS: Offspring of fathers who had a myocardial infarction tended to have a significantly raised level of Lp(a) (p < 0.001) compared with those without parental history. None of the other lipoprotein variables we examined exhibited a significant difference between the two groups of subjects. CONCLUSION: The offspring of fathers with early myocardial infarction have higher mean values of Lp(a) than control subjects suggesting that this lipid variable may strongly predispose to CAD. |
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Authors:
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S M Shah; K A Karira; Salahuddin; M S Soomro; S Ghafoor |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: JPMA. The Journal of the Pakistan Medical Association Volume: 51 ISSN: 0030-9982 ISO Abbreviation: J Pak Med Assoc Publication Date: 2001 May |
Date Detail:
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Created Date: 2001-07-24 Completed Date: 2001-08-23 Revised Date: 2008-02-12 |
Medline Journal Info:
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Nlm Unique ID: 7501162 Medline TA: J Pak Med Assoc Country: Pakistan |
Other Details:
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Languages: eng Pagination: 180-3 Citation Subset: IM |
Affiliation:
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Department of Biochemistry, Kyber Medical College, Peshawar. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Child Female Genetic Predisposition to Disease / genetics Humans Lipoprotein(a) / blood* Male Myocardial Infarction / blood, genetics* Risk Factors |
| Chemical | |
Reg. No./Substance:
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0/Lipoprotein(a) |
| Comments/Corrections | |
Erratum In:
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J Pak Med Assoc 2001 Dec;51(12):454 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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