| Serum lipids of pemphigus foliaceus patients on long-term glucocorticoid therapy. | |
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MedLine Citation:
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PMID: 12715056 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Endemic pemphigus foliaceus, and long-term corticotherapy may affect serum lipid levels. The aim of this study was to compare serum lipids of pemphigus foliaceus patients on glucocorticoid therapy to a healthy control group. Fifteen patients receiving prednisone (0.33 +/- 0.22 mg/kg) for at least 12 months and 15 controls were submitted to 48-h food intake records, anthropometry, and biochemical measurements. Data were compared by chi2, Mann-Whitney and Student "t" tests. The groups were matched for gender, age, weight, body mass index, arm circumference and triceps skin fold. No differences were observed in relation to energy, fat, protein and carbohydrate daily intakes, total cholesterol, HDL, LDL, uric acid, and serum creatinine levels. Pemphigus foliaceus patients had higher triglyceride [159 (64-371) vs. 100 (45-133) mg/dl], VLDL [32 (13-74) vs. 20 (9-114) mg/dl] and ESR [44 (9-87) vs. 7 (1-30) mm/h] levels than controls, probably due to metabolic effects of inflammatory disease and corticotherapy. |
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Authors:
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Selma Freire de Carvalho da Cunha; Vitorino Modesto dos Santos; Jacqueline Pontes Monteiro; Tácio Pierre Sousa Ferreira; Jenner Arruda Modesto dos Santos; Taciana Arruda Modesto dos Santos; Daniel Ferreira da Cunha |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2003-04-22 |
Journal Detail:
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Title: Revista da Sociedade Brasileira de Medicina Tropical Volume: 36 ISSN: 0037-8682 ISO Abbreviation: Rev. Soc. Bras. Med. Trop. Publication Date: 2003 Jan-Feb |
Date Detail:
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Created Date: 2003-04-25 Completed Date: 2003-07-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7507456 Medline TA: Rev Soc Bras Med Trop Country: Brazil |
Other Details:
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Languages: eng Pagination: 1-4 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine, Faculdade de Medicina do Triângulo Mineiro, Uberaba. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Blood Sedimentation
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drug effects Case-Control Studies Female Glucocorticoids / therapeutic use* Humans Lipids / blood* Male Pemphigus / blood*, drug therapy Prednisone / therapeutic use* Statistics, Nonparametric Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Glucocorticoids; 0/Lipids; 53-03-2/Prednisone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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