| Serum lipids and modernization in coastal and highland Papua New Guinea. | |
| | |
MedLine Citation:
|
PMID: 8956625 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Previous studies in Melanesians of Papua New Guinea have documented low serum cholesterol concentrations with no age-related rise and a virtual absence of coronary heart disease. However, because of recent reports of the emergence of coronary heart disease in this population, serum lipid concentrations in adults aged > or = 25 years in three coastal (n = 1,489 and three highland (n = 388) village communities at different stages of modernization were examined as part of a survey undertaken in 1991. Total cholesterol concentrations were clearly higher than were levels recorded in earlier studies. Moreover, age-related increases in total cholesterol, low density lipoprotein cholesterol (LDL cholesterol), high density lipoprotein cholesterol (HDL cholesterol), and triglycerides (in women) were apparent. Mean total cholesterol levels in an urban community with a high risk of diabetes were similar to those observed in Australians, while HDL cholesterol concentrations were lower. Total cholesterol and LDL cholesterol levels were higher in urban coastal and periurban highland subjects than in their rural counterparts. Prevalence of hypercholesterolemia (> or = 5.2 mmol/liter) varied from 16% in rural highlanders to 56% in urban coastal subjects. Sex, age, village, body mass index, fat distribution, glucose intolerance, physical activity, and an index of relative modernity all contributed to variations in cholesterol and triglyceride concentrations. These results show that Papua New Guineans are by no means protected from dyslipidemia and serve warning that, unless effective preventative strategies can be developed, this and similar rapidly developing populations can expect an increasing incidence of coronary heart disease. |
| | |
Authors:
|
A M Hodge; G K Dowse; R T Erasmus; R A Spark; K Nathaniel; P Z Zimmet; M P Alpers |
Related Documents
:
|
1316885 - Dietary modulators of lipid metabolism in the indian diet-heart study (i.d.h.s.). 16280425 - Individual variability in cardiovascular disease risk factor responses to low-fat and l... 2192875 - Role of circulating high-density lipoprotein and triglycerides in coronary artery disea... 14613505 - Reproducibility of the serum lipid response to coffee oil in healthy volunteers. 15528005 - Ethanol intake inhibits growth of the epithelium in the intestine of pregnant rats. 2751745 - Lipoproteins and apolipoproteins in young male survivors of myocardial infarction. |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: American journal of epidemiology Volume: 144 ISSN: 0002-9262 ISO Abbreviation: Am. J. Epidemiol. Publication Date: 1996 Dec |
Date Detail:
|
Created Date: 1997-01-07 Completed Date: 1997-01-07 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7910653 Medline TA: Am J Epidemiol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1129-42 Citation Subset: IM |
Affiliation:
|
International Diabetes Institute, Melbourne, Victoria, Australia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acculturation* Adult Epidemiologic Methods Female Humans Hypercholesterolemia / epidemiology*, etiology Lipids / blood* Male Middle Aged New Guinea / epidemiology Prevalence |
| Chemical | |
Reg. No./Substance:
|
0/Lipids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Family history and risk of colorectal cancer in the multiethnic population of Hawaii.
Next Document: Body size and fat distribution as predictors of stroke among US men.