Document Detail

Serum lipids and lipoproteins and carotid artery wall intima-media thickness in a population of menopausal women.
MedLine Citation:
PMID:  10486793     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To assess the influence of aging on serum lipids and lipoproteins in menopausal women and to determine whether arterial hypertension can determine carotid artery wall intima-media thickening in these subjects. DESIGN: We assessed cholesterol, low density lipoprotein cholesterol, triglycerides, and carotid artery wall intima-media thickness in 729 menopausal women aged 40-65 years, divided into four age groups (40-45 years, 46-50 years, 51-55 years, and 56-60 years). RESULTS: Serum lipids and lipoproteins rose progressively in the different age groups. Carotid wall thickness also increased and was more evident when accompanied by arterial hypertension. CONCLUSIONS: Our results suggest that elevated serum lipids and lipoproteins are interrelated with increased carotid artery wall intima-media thickness. Moreover, they showed the benefits of hormone replacement therapy.
S S Signorelli; S Salvatore; D Luigi; C M Pia; P Giuseppe; C Sarina
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article    
Journal Detail:
Title:  Menopause (New York, N.Y.)     Volume:  6     ISSN:  1072-3714     ISO Abbreviation:  Menopause     Publication Date:  1999  
Date Detail:
Created Date:  1999-10-15     Completed Date:  1999-10-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9433353     Medline TA:  Menopause     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  230-2     Citation Subset:  IM    
Department of Internal Medicine A. Francaviglia, University of Catania, Italy.
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MeSH Terms
Age Distribution
Cardiovascular Diseases / etiology,  prevention & control
Carotid Arteries / ultrasonography*
Cholesterol / blood*
Evaluation Studies as Topic
Fibrinogen / analysis
Hormone Replacement Therapy
Hypertension / etiology
Lipoproteins, LDL / blood*
Menopause / physiology*
Middle Aged
Risk Assessment
Triglycerides / blood*
Tunica Intima / ultrasonography*
Reg. No./Substance:
0/Lipoproteins, LDL; 0/Triglycerides; 57-88-5/Cholesterol; 9001-32-5/Fibrinogen

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