| Serum lipids in north Indian children treated for kawasaki disease. | |
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MedLine Citation:
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PMID: 16272772 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A prospective cross sectional analysis of serum lipids was carried out in 20 children aged between 1.3 and 16 years with Kawasaki disease (KD). The controls were siblings of other patients. The mean interval between diagnosis of the disease and time of assay was 2.6 years (range 0.41 to 6 years). Standard biochemical methods were employed for determination of various components of the lipid profiles. There were significant differences in high-density lipoprotein cholesterol (HDL-C) (40.37 +/- 12.0 mg/dL versus 53.49 +/- 4.31 mg/dL, P < 0.001) and low-density lipoprotein cholesterol (LDL-C) concentrations (77.76 +/- 26.25 mg/dL versus 57.7 +/- 23.2 mg/dL, P < 0.05) between the cases and controls. Lower HDL-C levels persisted at 1-3 and more than 3 years of disease duration. No significant differences were seen in the values of other parameters in the lipidogram, such as total cholesterol (TC), triglycerides (TG), and very low-density lipoprotein cholesterol (VLDL-C). Premature atherosclerosis that occurs in KD may be secondary to these lipid metabolism abnormalities. |
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Authors:
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Aurobindo Mitra; Surjit Singh; Devidayal; Madhu Khullar |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: International heart journal Volume: 46 ISSN: 1349-2365 ISO Abbreviation: - Publication Date: 2005 Sep |
Date Detail:
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Created Date: 2005-11-07 Completed Date: 2006-03-10 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 101244240 Medline TA: Int Heart J Country: Japan |
Other Details:
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Languages: eng Pagination: 811-7 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Advanced Pediatric Center, Postgraduate Institute of Medical Education and Research, Chandigarh, India. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Case-Control Studies Child Child, Preschool Cholesterol / blood Cholesterol, HDL / blood Cholesterol, LDL / blood Cross-Sectional Studies Female Humans Infant Lipid Metabolism* Lipids / blood* Male Mucocutaneous Lymph Node Syndrome / blood*, metabolism Prospective Studies Reproducibility of Results Triglycerides / blood |
| Chemical | |
Reg. No./Substance:
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0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Lipids; 0/Triglycerides; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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