Document Detail


Serum lipid and lipoprotein concentration in coronary heart disease.
MedLine Citation:
PMID:  4053617     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The relationship between serum lipid and lipoprotein concentration and the severity of coronary artery disease assessed by cineangiography was studied in 38 male patients, aged 44 +/- 11.5 years. According to luminal diameter narrowing of 3 major coronary arteries, the patients were divided into 3 groups: group A -- 10 patients with a normal coronarographic finding; group B -- 8 patients with a 26 to 50% coronary artery stenosis; group C -- 20 men with coronary stenosis exceeding 51%. With the exception of Apo B which in patients of group B was slightly elevated (p less than 0.05), there was no difference in serum lipid and lipoprotein levels between patients of group A and B. Patients of group C had significantly increased Apo B and triglyceride levels and a decreased high density lipoproteins (HDL) cholesterol/total cholesterol ratio in comparison with the control group. In group C, a linear correlation was found between the number of affected major coronary arteries and the serum Apo B level. The results suggest that determination of Apo B, triglycerides and the HDL cholesterol/total cholesterol ratio contributes to assessing the severity of coronary heart disease.
Authors:
O Luknárová; O Kusá; I Riecanský; J Zelenay
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cor et vasa     Volume:  27     ISSN:  0010-8650     ISO Abbreviation:  Cor Vasa     Publication Date:  1985  
Date Detail:
Created Date:  1985-11-25     Completed Date:  1985-11-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372614     Medline TA:  Cor Vasa     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  266-71     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Apolipoproteins B / blood
Coronary Disease / blood*,  physiopathology
Humans
Lipids / blood*
Lipoproteins / blood*
Male
Middle Aged
Chemical
Reg. No./Substance:
0/Apolipoproteins B; 0/Lipids; 0/Lipoproteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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