Document Detail


Serum lipid fatty acids, phonological processing, and reading in children with oral clefts.
MedLine Citation:
PMID:  16260127     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Reading skill is suggested to be related to phonological processing ability and polyunsaturated fatty acids (PUFAs). Here we investigated whether fatty acids (FAs) are related to phonological processing, whether the relations between PUFAs and reading generalize to other FAs, whether these relations are mediated by phonological processing, and whether relations of FAs are specific for language-related functions. Blood samples of 49 ten-year-old children with oral clefts were collected for FA proportion analysis in serum cholesteryl esters and phospholipids. On the same day, they performed tasks of phonological processing, reading, and both verbal and nonverbal intelligence. Sequential regression analyses (adjusted for age, gender, and cleft type) showed that phonological processing was inversely related to myristic acid in phospholipids and positively related to eicosapentaenoic acid in cholesteryl esters. Reading was inversely related to palmitoleic and gammalinolenic acids in phospholipids. The relations between FAs and reading were not mediated by phonological processing and FAs related only to language-related functions.
Authors:
M Laasonen; A T Erkkilä; E Isotalo; J J Pulkkinen; M-L Haapanen; V Virsu
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2005-11-02
Journal Detail:
Title:  Prostaglandins, leukotrienes, and essential fatty acids     Volume:  74     ISSN:  0952-3278     ISO Abbreviation:  Prostaglandins Leukot. Essent. Fatty Acids     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2005-12-12     Completed Date:  2006-02-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8802730     Medline TA:  Prostaglandins Leukot Essent Fatty Acids     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  7-16     Citation Subset:  IM    
Affiliation:
Department of Psychology, University of Helsinki, FIN-00014 Helsinki, Finland. Marja.Laasonen@helsinki.fi
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MeSH Terms
Descriptor/Qualifier:
Auditory Perception / physiology*
Child
Cholesterol Esters / blood,  chemistry
Cleft Lip / blood*,  psychology
Cleft Palate / blood*,  psychology
Dyslexia / blood,  psychology
Fatty Acids / blood*
Fatty Acids, Monounsaturated / blood
Fatty Acids, Unsaturated / blood
Female
Humans
Intelligence / physiology
Intelligence Tests
Language Tests
Lipids / blood*,  chemistry
Male
Phospholipids / blood,  chemistry
Psychometrics
Reading*
Speech Perception / physiology
Task Performance and Analysis
Chemical
Reg. No./Substance:
0/Cholesterol Esters; 0/Fatty Acids; 0/Fatty Acids, Monounsaturated; 0/Fatty Acids, Unsaturated; 0/Lipids; 0/Phospholipids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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