Document Detail


Serum levels of marine-derived n-3 fatty acids in Icelanders, Japanese, Koreans, and Americans--a descriptive epidemiologic study.
MedLine Citation:
PMID:  22658580     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In the 1990s Iceland and Japan were known as countries with high fish consumption whereas coronary heart disease (CHD) mortality in Iceland was high and that in Japan was low among developed countries. We described recent data fish consumption and CHD mortality from publicly available data. We also measured CHD risk factors and serum levels of marine-derived n-3 and other fatty acids from population-based samples of 1324 men in Iceland, Japan, South Korea, and the US. CHD mortality in men in Iceland was almost 3 times as high as that in Japan and South Korea. Generally, a profile of CHD risk factors in Icelanders compared to Japanese was more favorable. Serum marine-derived n-3 fatty acids in Iceland were significantly lower than in Japan and South Korea but significantly higher than in the US.
Authors:
Akira Sekikawa; Laufey Steingrimsdottir; Hirotsugu Ueshima; Chol Shin; J David Curb; Rhobert W Evans; Alda M Hauksdottir; Aya Kadota; Jina Choo; Kamal Masaki; Bolli Thorsson; Lenore J Launer; Melisa E Garcia; Hiroshi Maegawa; Bradley J Willcox; Gudny Eiriksdottir; Akira Fujiyoshi; Katsuyuki Miura; Tamara B Harris; Lewis H Kuller; Vilmundur Gudnason
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't     Date:  2012-05-31
Journal Detail:
Title:  Prostaglandins, leukotrienes, and essential fatty acids     Volume:  87     ISSN:  1532-2823     ISO Abbreviation:  Prostaglandins Leukot. Essent. Fatty Acids     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-07-24     Completed Date:  2013-01-22     Revised Date:  2013-07-08    
Medline Journal Info:
Nlm Unique ID:  8802730     Medline TA:  Prostaglandins Leukot Essent Fatty Acids     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  11-6     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
Affiliation:
University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA 15213, USA. akira@pitt.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Asian Americans
Cholesterol / blood
Coronary Disease / blood*,  ethnology,  etiology,  mortality
Fatty Acids, Omega-3 / blood*
Humans
Iceland / epidemiology
Japan / epidemiology,  ethnology
Male
Middle Aged
Republic of Korea / epidemiology
Risk Factors
Seafood
United States / epidemiology
Grant Support
ID/Acronym/Agency:
N01AG12100/AG/NIA NIH HHS; N01AG12100/AG/NIA NIH HHS; R01 HL068200/HL/NHLBI NIH HHS; R01 HL071561/HL/NHLBI NIH HHS; R01HL071561/HL/NHLBI NIH HHS; R01HL68200/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Fatty Acids, Omega-3; 57-88-5/Cholesterol
Comments/Corrections

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