| Serum levels of immunoreactive somatomedin A in the rat: some developmental aspects. | |
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MedLine Citation:
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PMID: 7389669 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Immunoreactive somatomedin A (SMA) was determined in rat serum collected at 20 days of gestation and at 5, 15, 25, and 50 days of postnatal age. Adult levels were shown to be GH dependent. A rapid rise in immunoreactive SMA was observed after 15 days of postnatal age, and this was attributed to the triggering of the SMA-GH regulatory system by nutritional factors at weaning. Circulating levels of immunoreactive SMA were reduced during early development and in pregnancy, raising the possibility that early growth is regulated by an embryonic form of SM which is not detected by the SMA RIA. |
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Authors:
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V R Sara; K Hall; P E Lins; L Fryklund |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Endocrinology Volume: 107 ISSN: 0013-7227 ISO Abbreviation: Endocrinology Publication Date: 1980 Aug |
Date Detail:
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Created Date: 1980-09-26 Completed Date: 1980-09-26 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0375040 Medline TA: Endocrinology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 622-5 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aging Animals Female Fetal Blood / analysis Fetus Growth Hormone / pharmacology Hypophysectomy Insulin-Like Growth Factor II* Male Pregnancy Rats Sexual Maturation Somatomedins / blood* |
| Chemical | |
Reg. No./Substance:
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0/Somatomedins; 67763-97-7/Insulin-Like Growth Factor II; 9002-72-6/Growth Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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