Document Detail


Serum leptin levels in preterm, healthy and sick-term newborns.
MedLine Citation:
PMID:  12607479     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Leptin, a hormone that signals the brain about the status of body (fat) energy stores, has recently been shown to play a role in the regulation of several hypothalamic pituitary axes, including the growth hormone axis. To investigate a potential association of serum leptin concentrations and clinical condition in preterm, sick term and healthy term newborns, serum leptin concentrations were evaluated in 104 newborns. Twenty-eight of them were healthy term (18 males and 10 females; gestational age, 37-42 weeks), 21 were sick term (12 males and 9 females; gestational age, 37-42 weeks) and 55 were preterm neonates (35 males and 20 females; gestational age: 26-37 weeks). Leptin values correlate positively with birth weight, birth length, head circumference, waist circumference, hip circumference, body surface, weight/length ratio, and gestational age (r = 0.38, 0.42, 0.29, 0.21, 0.29, 0.40, 0.31 and 0.28), respectively. The concentrations of leptin are statistically significantly higher (p < 0.05) in term neonates (3.02 +/- 2.94 ng/ml) than preterm neonates (1.93 +/- 2.21 ng/ml). Female infants also have significantly higher (p < 0.05) serum leptin values than male infants in preterm and healthy term groups. We also found leptin present in venous blood after 26 weeks of gestation.
Authors:
Pen-Hua Su; Shu-Li Wang; Jia-Yuh Chen; Cheng-Pin Chang Lai; Shu-Hua Jian
Related Documents :
20331899 - Inhaled nitric oxide in preterm infants: a systematic review and individual patient dat...
19796729 - Prediction of preterm birth: cervical sonography.
22427749 - Planned vaginal birth or elective repeat caesarean: patient preference restricted cohor...
14601269 - The effect of glucocorticoid therapy in preventing early neonatal complications in pret...
2602039 - Cerebral artery flow velocity acceleration and deceleration characteristics in newborn ...
19375569 - Predictive value of combined amniotic fluid proteomic biomarkers and interleukin-6 in p...
281629 - Detection of hearing loss in infancy.
8446099 - Infant mortality--united states, 1990.
7872039 - Suicide in south africa. an analysis of nationally registered mortality data for 1984-1...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi     Volume:  43     ISSN:  1608-8115     ISO Abbreviation:  Acta Paediatr Taiwan     Publication Date:    2002 Sep-Oct
Date Detail:
Created Date:  2003-02-27     Completed Date:  2003-03-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  100958202     Medline TA:  Acta Paediatr Taiwan     Country:  China (Republic: 1949- )    
Other Details:
Languages:  eng     Pagination:  249-54     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Chung Shan Medical University Hospital, No. 110, Sec. 1, Chien-Kuo North. Road, Taichung 402, Taiwan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Birth Weight
Body Mass Index
Female
Gestational Age
Humans
Infant, Newborn
Infant, Premature
Leptin / blood*
Male
Chemical
Reg. No./Substance:
0/Leptin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Serum gamma-glutamyl transpeptidase activity and bile acids in normal Taiwanese infants.
Next Document:  Changing position does not improve the efficacy of conventional phototherapy.