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Serum leptin level in the first trimester in ectopic versus normal pregnancies.
MedLine Citation:
PMID:  21483996     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
OBJECTIVE: To determine whether maternal serum leptin level is different or not in ectopic and normal pregnancy.
METHODS: In this cross sectional study, we included 47 women with normal pregnancy (group A), and 47 women with ectopic pregnancy (group B) attending the Department of Obstetrics and Gynecology, Afzalipour Medical Centre, Kerman, Iran from January 2009 to February 2010. Previous history of miscarriage or ectopic pregnancy, </=25 body mass index (BMI), </=19 kg/m2, using drugs during pregnancy except for multivitamin and folic acid, unstable conditions requiring emergency laparatomy, and cigarette smoking were considered as exclusion criteria. The maximum gestational age in both groups was 8 weeks. Maternal serum leptin level was determined using enzyme-linked immunosorbent assay kit. Data were analyzed using one-way analysis of variance.
RESULTS: There were no statistically significant differences between the 2 groups in maternal age, gestational age, and body mass index. Women in group B (median [range]: 30.93 [14.8-84.2]) showed significantly higher serum leptin level in comparison with group A (median [range]: 32.74 [8.4-8.61]).
CONCLUSION: Serum leptin level in the first trimester of pregnancy may be a useful marker in the differential diagnosis of ectopic pregnancy.
Authors:
Zahra Kamyabi; Ghazaal Mansouri; Fatemeh Azizzian
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Saudi medical journal     Volume:  32     ISSN:  0379-5284     ISO Abbreviation:  Saudi Med J     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-04-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7909441     Medline TA:  Saudi Med J     Country:  Saudi Arabia    
Other Details:
Languages:  eng     Pagination:  376-8     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Afzalipour Medical Centre, Kerman University of Medical Sciences, Kerman 7616913911, Iran. Tel. +98 (341) 3222250 Ext. 306. Fax. +98 (341) 2456269. E-mail: zkamyabi@yahoo.com.
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